Below is Dave Campbell's Texas Football's and TexasFootball.com's final regular season ranking for Class 5A. The rankings will have one final adjustment after the state title games.
| 2012 Week Ten Rankings | ||||
| CLASS 5A |
| Rank | School (Last week) | 2012 Overall/District Record | Previous result |
| 1 | Katy (1) | 10-0/7-0 | W: 41-6, Houston Memorial |
| 2 | Cibolo Steele (2) | 10-0/5-0 | W: 42-14, SA Southwest |
| 3 | DeSoto (3) | 10-0/6-0 | W: 37-23, Mansfield |
| 4 | Coppell (4) | 10-0/5-0 | W: 41-3, Lewisville |
| 5 | Allen (5) | 9-1/5-0 | W: 35-34, Plano |
| 6 | Southlake Carroll (6) | 9-1/7-0 | W: 56-17, Haltom |
| 7 | Dallas Skyline (7) | 9-1/7-0 | W: 63-20, Richardson Berkner |
| 8 | Hewitt Midway (8) | 10-0/7-0 | W: 34-16, Belton |
| 9 | La Porte (9) | 9-1/6-0 | W: 37-33, PA Memorial |
| 10 | Abilene (10) | 10-0/8-0 | W: 28-21, Midland |
| 11 | Euless Trinity (11) | 8-2/7-0 | W: 71-6, Carrollton Turner |
| 12 | Mesquite (12) | 10-0/6-0 | Open |
| 13 | Smithson Valley (13) | 10-0/5-0 | W: 35-7, SA Wagner |
| 14 | Manvel (14) | 9-1/7-0 | W: 61-20, South Houston |
| 15 | GP North Shore (15) | 9-1/5-1 | W: 14-7, Deer Park |
| 16 | Arlington Bowie (16) | 9-1/7-0 | W: 44-26, Arlington Martin |
| 17 | Lake Travis (18) | 9-1/6-0 | Bye |
| 18 | Spring Westfield (19) | 10-0/8-0 | W: 28-14, Spring Dekaney |
| 19 | SA Brandeis (20) | 9-1/8-0 | W: 63-17, SA Holmes |
| 20 | Colleyville Heritage (21) | 9-1/6-1 | W: 35-30, Hurst L.D. Bell |
| 21 | SA Madison (22) | 8-2/6-0 | W: 35-2, SA Johnson |
| 22 | A&M Consolidated (23) | 8-2/5-1 | Bye |
| 23 | Houston Lamar (25) | 10-0/6-0 | W: 48-0, Houston Chavez |
| 24 | PA Memorial (24) | 8-2/4-2 | L: 37-33, La Porte |
| 25 | Mission Sharyland (N/A) | 10-0/8-0 | W: 69-0, Edinburg Vela |
Dropped out: No. 17 Arlington Martin (L: 44-26, Arlington Bowie)
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