Below is Dave Campbell's Texas Football's and TexasFootball.com's final regular season ranking for Class 4A. The rankings will have one final adjustment after the state title games.
| 2012 Week Ten Rankings | ||||
| CLASS 4A |
| Rank | School (Last week) | 2012 Overall/District Record | Previous result |
| 1 | Pearland Dawson (1) | 10-0/7-0 | W: 56-14, Galena Park |
| 2 | Tyler John Tyler (2) | 9-1/5-0 | W: 45-38, Whitehouse |
| 3 | Denton Guyer (3) | 8-2/7-0 | W: 62-8, FW Brewer |
| 4 | Aledo (4) | 9-1/7-0 | W: 58-6, FW Trimble Tech |
| 5 | Cedar Park (5) | 8-2/6-0 | W: 35-14, Dripping Springs |
| 6 | Leander (6) | 9-1/5-1 | W: 56-14, Marble Falls |
| 7 | Highland Park (8) | 9-1/7-0 | W: 56-7, Terrell |
| 8 | Wichita Falls Rider (9) | 8-2/6-1 | W: 49-0, Wichita Falls |
| 9 | Nederland (10) | 9-1/7-0 | W: 45-14, Beaumont Central |
| 10 | Humble Summer Creek (12) | 10-0/8-0 | W: 45-7, Dayton |
| 11 | Lancaster (13) | 9-1/6-1 | W: 48-17, Mansfield Summit |
| 12 | Prosper (7) | 8-2/5-2 | L: 21-7, Frisco |
| 13 | Angleton (14) | 8-2/5-1 | W: 31-6, Rosenberg Terry |
| 14 | Whitehouse (15) | 9-1/4-1 | L: 45-38, John Tyler |
| 15 | Amarillo (16) | 8-2/5-0 | W: 55-14, Dumas |
| 16 | Lucas Lovejoy (17) | 10-0/7-0 | W: 58-32, Wylie East |
| 17 | Dayton (11) | 9-1/7-1 | L: 45-7, Summer Creek |
| 18 | Sherman (18) | 8-2/6-1 | W: 27-14, Greenville |
| 19 | Brenham (19) | 9-1/8-0 | W: 56-17, Caney Creek |
| 20 | PL Calhoun (21) | 9-0/6-0 | Bye |
| 21 | Wolfforth Frenship (22) | 9-1/5-0 | W: 37-7, Plainview |
| 22 | CC Flour Bluff (23) | 10-0/7-0 | W: 37-10, Laredo Nixon |
| 23 | Georgetown (24) | 10-0/7-0 | W: 54-28, Bastrop |
| 24 | FB Marshall (25) | 10-0/7-0 | W: 52-13, FB Willowridge |
| 25 | SA Brennan (N/A) | 10-0/6-0 | Bye |
Dropped out: No. 20 Dallas South Oak Cliff (L: 20-19, Dallas Kimball)
