Below is Dave Campbell's Texas Football's and TexasFootball.com's final regular season ranking for Class 2A-DII. The rankings will have one final adjustment after the state title games.
| 2012 Week Ten Rankings | ||||
| CLASS 2A-DII |
| Rank | School (Last week) | 2012 Overall/District Record | Previous result |
| 1 | Refugio (1) | 10-0/7-0 | W, 84-0, Skidmore-Tynan |
| 2 | East Bernard (2) | 10-0/6-0 | W, 49-0, Danbury |
| 3 | Hughes Springs (3) | 10-0/7-0 | W, 55-26, Waskom |
| 4 | Centerville (4) | 10-0/7-0 | W, 56-0, Bruceville-Eddy |
| 5 | Cisco (5) | 9-1/5-0 | W, 40-7, Ballinger |
| 6 | Lexington (6) | 8-2/5-0 | W, 21-7, Schulenburg |
| 7 | Gunter (7) | 9-1/5-0 | Idle |
| 8 | Arp (8) | 8-2/6-0 | W, 51-14, Winona |
| 9 | Nocona (9) | 10-0/5-0 | W, 20-0, Henrietta |
| 10 | Corsicana Mildred (NR) | 9-1/7-0 | W, 83-0, Scurry-Rosser |
Dropped out: No. 10 Abernathy (L, 21-14, Post)
